品牌 | SOLARBIO/索萊寶 | 貨號(hào) | K106612P |
---|---|---|---|
規(guī)格 | 50ul/100ul | 供貨周期 | 現(xiàn)貨 |
主要用途 | WB | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) |
Anti-NR3C2 Polyclonal Antibody
英文名稱(chēng) | Anti-NR3C2 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | MCR;MLR;MR;NR3C2VIT |
應(yīng)用 | WB |
稀釋比例 | WB 1:500-2000. |
交叉反應(yīng) | Human Mouse |
蛋白分子量 | 107kDa |
Gene ID | 4306 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human NR3C2 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human NR3C2 |
Subcellular Locations | Cytoplasm Nucleus |
Swiss Prot | P08235 |
克隆類(lèi)型 | Polyclonal Antibody |
背景資料 | This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. |