品牌 | SOLARBIO/索萊寶 | 貨號(hào) | K106613P |
---|---|---|---|
規(guī)格 | 50ul/100ul | 供貨周期 | 現(xiàn)貨 |
主要用途 | WB | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) |
英文名稱 | Anti-LIFR Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | CD118;LIF-R;SJS2;STWS;SWS |
應(yīng)用 | WB |
稀釋比例 | WB 1:500-2000. |
交叉反應(yīng) | Human |
蛋白分子量 | 115kDa |
Gene ID | 3977 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human LIFR |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human LIFR |
Subcellular Locations | Cytoplasm Cell membrane |
Swiss Prot | P42702 |
克隆類型 | Polyclonal Antibody |
背景資料 | This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. |