品牌 | SOLARBIO/索萊寶 | 貨號(hào) | K106504P |
---|---|---|---|
規(guī)格 | 50ul/100ul | 供貨周期 | 現(xiàn)貨 |
主要用途 | WB | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) |
Anti-Delta4 Polyclonal Antibody
英文名稱 | Anti-Delta4 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | DLL4;AOS6;DLL 4;hdelta2;MGC126344 |
應(yīng)用 | WB |
稀釋比例 | WB 1:3000. |
交叉反應(yīng) | Human Mouse Rat |
蛋白分子量 | 75kDa |
Gene ID | 54567 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human Delta4 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human Delta4 |
Subcellular Locations | Cell membrane |
Swiss Prot | Q9NR61 |
克隆類型 | Polyclonal Antibody |
背景資料 | The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium. |