品牌 | SOLARBIO/索萊寶 | 貨號 | K106473P |
---|---|---|---|
規(guī)格 | 50ul/100ul | 供貨周期 | 現(xiàn)貨 |
主要用途 | WB | 應用領域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產業(yè),農業(yè) |
Anti-IL12 Polyclonal Antibody
英文名稱 | Anti-IL12 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | IL-12A;CLMF p35;IL-12 subunit p35;NKSF1;IL12A |
應用 | WB |
稀釋比例 | WB 1:3000. |
交叉反應 | Human Mouse Rat |
蛋白分子量 | 52kDa |
Gene ID | 3592 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human IL12 |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human IL12 |
Subcellular Locations | Cell membrane Secreted |
Swiss Prot | P29459 |
克隆類型 | Polyclonal Antibody |
背景資料 | IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |