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  • Anti-PARP Monoclonal Antibody
產(chǎn)品名稱：

Anti-PARP Monoclonal Antibody
產(chǎn)品品牌： SOLARBIO/索萊寶 價(jià)格：
廠商性質(zhì)： 生產(chǎn)廠家 產(chǎn)品時(shí)間： 2022-08-15
Anti-PARP Monoclonal Antibody
應(yīng)用 WB IHC
稀釋比例WB 1:1000-3000. IHC 1:200-500.
交叉反應(yīng)Human

產(chǎn)品概述

品牌SOLARBIO/索萊寶貨號K200026M
規(guī)格50ul/100ul供貨周期現(xiàn)貨
主要用途WB IHC應(yīng)用領(lǐng)域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè)

Anti-PARP Monoclonal Antibody 

英文名稱Anti-PARP Monoclonal Antibody
宿主Mouse
別名PARP-1; Poly(ADP ribose) polymerase 1; sPARP1;ADPRT1; ADP ribosyltransferase NAD(+)
應(yīng)用WB IHC
稀釋比例WB 1:1000-3000. IHC 1:200-500.
交叉反應(yīng)Human
蛋白分子量116kDa
Gene ID142
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG1
免疫原A synthetic peptide coupled to KLH
性狀液體
Public Immunogen Range

A synthetic peptide coupled to KLH

Subcellular LocationsNucleus
Swiss ProtP09874
克隆號M3
克隆類型Monoclonal Antibody
背景資料Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.

 

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